Whole exome sequencing identifies novel genes for fetal hemoglobin response to hydroxyurea in children with sickle cell anemia. [electronic resource]
Producer: 20150624Description: e110740 p. digitalISSN:- 1932-6203
- Anemia, Sickle Cell -- drug therapy
- Child
- Cohort Studies
- DNA-Binding Proteins
- Dose-Response Relationship, Drug
- Exome -- drug effects
- Fetal Hemoglobin -- metabolism
- Genomics
- Humans
- Hydroxyurea -- adverse effects
- Maximum Tolerated Dose
- Open Reading Frames -- genetics
- Phenotype
- Prospective Studies
- Sequence Analysis, DNA
- Transcription Factors -- genetics
- Treatment Outcome
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Publication Type: Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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