Angiotensin II induces interleukin-1β-mediated islet inflammation and β-cell dysfunction independently of vasoconstrictive effects. [electronic resource]
Producer: 20150522Description: 1273-83 p. digitalISSN:- 1939-327X
- Angiotensin II -- pharmacology
- Animals
- Apoptosis -- drug effects
- Blood Glucose -- metabolism
- Chemokine CCL2 -- metabolism
- Diabetes Mellitus, Type 2 -- metabolism
- Diet, High-Fat
- Humans
- Inflammation -- chemically induced
- Insulin -- metabolism
- Insulin Secretion
- Interleukin-1beta -- metabolism
- Islets of Langerhans -- drug effects
- Mice
- Mitochondria -- drug effects
- Renin-Angiotensin System -- physiology
- Vasoconstriction -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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