Induction of sustained hypercholesterolemia by single adeno-associated virus-mediated gene transfer of mutant hPCSK9. [electronic resource]
Producer: 20150223Description: 50-9 p. digitalISSN:- 1524-4636
- Animals
- Aorta -- enzymology
- Aortic Diseases -- blood
- Apolipoproteins E -- deficiency
- Atherosclerosis -- blood
- Biomarkers -- blood
- Cholesterol -- blood
- Dependovirus -- genetics
- Diet, High-Fat
- Disease Models, Animal
- Gene Transfer Techniques
- Genetic Vectors
- Humans
- Hypercholesterolemia -- blood
- Male
- Mice, 129 Strain
- Mice, Inbred C57BL
- Mice, Knockout
- Mutation
- Plaque, Atherosclerotic
- Proprotein Convertase 9
- Proprotein Convertases -- genetics
- Serine Endopeptidases -- genetics
- Time Factors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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