HTLV-1 tax stabilizes MCL-1 via TRAF6-dependent K63-linked polyubiquitination to promote cell survival and transformation. [electronic resource]
Producer: 20151218Description: e1004458 p. digitalISSN:- 1553-7374
- Animals
- Apoptosis -- physiology
- Cell Survival -- physiology
- Cell Transformation, Neoplastic -- metabolism
- DNA Damage
- Gene Products, tax -- metabolism
- Human T-lymphotropic virus 1 -- isolation & purification
- Humans
- Lysine -- metabolism
- Mass Spectrometry -- methods
- Mice
- Myeloid Cell Leukemia Sequence 1 Protein -- metabolism
- NF-kappa B -- metabolism
- Polyubiquitin -- metabolism
- TNF Receptor-Associated Factor 6 -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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