Allosteric activation of the RNF146 ubiquitin ligase by a poly(ADP-ribosyl)ation signal. [electronic resource]
Producer: 20150219Description: 223-6 p. digitalISSN:- 1476-4687
- Adenosine Diphosphate Ribose -- chemistry
- Allosteric Regulation
- Animals
- Biocatalysis
- Crystallography, X-Ray
- Enzyme Activation
- Humans
- Ligands
- Mice
- Models, Molecular
- Poly Adenosine Diphosphate Ribose -- chemistry
- Protein Binding
- Protein Processing, Post-Translational
- Protein Structure, Tertiary
- Substrate Specificity
- Tankyrases -- metabolism
- Ubiquitin-Conjugating Enzymes -- chemistry
- Ubiquitin-Protein Ligases -- chemistry
- Ubiquitination
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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