Enhanced chondrogenesis of induced pluripotent stem cells from patients with neonatal-onset multisystem inflammatory disease occurs via the caspase 1-independent cAMP/protein kinase A/CREB pathway. [electronic resource]
Producer: 20150330Description: 302-14 p. digitalISSN:- 2326-5205
- Carrier Proteins -- genetics
- Caspase 1 -- physiology
- Cell Differentiation -- physiology
- Cells, Cultured
- Chondrocytes -- metabolism
- Chondrogenesis -- physiology
- Cryopyrin-Associated Periodic Syndromes -- genetics
- Cyclic AMP -- physiology
- Cyclic AMP Response Element-Binding Protein -- physiology
- Cyclic AMP-Dependent Protein Kinases -- physiology
- Glycosaminoglycans -- metabolism
- Humans
- In Vitro Techniques
- Inflammasomes -- chemistry
- Mutation -- genetics
- NLR Family, Pyrin Domain-Containing 3 Protein
- Phenotype
- Pluripotent Stem Cells -- pathology
- SOX9 Transcription Factor -- metabolism
- Signal Transduction -- physiology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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