AAV.shRNA-mediated downregulation of ROCK2 attenuates degeneration of dopaminergic neurons in toxin-induced models of Parkinson's disease in vitro and in vivo. [electronic resource]
Producer: 20150729Description: 150-62 p. digitalISSN:- 1095-953X
- 3,4-Dihydroxyphenylacetic Acid -- metabolism
- Adrenergic Agents -- toxicity
- Animals
- Dependovirus -- genetics
- Disease Models, Animal
- Dopaminergic Neurons -- metabolism
- Down-Regulation -- genetics
- Genetic Vectors -- physiology
- Homovanillic Acid
- Lim Kinases -- genetics
- Nerve Degeneration -- etiology
- Oxidopamine -- toxicity
- Parkinson Disease -- complications
- Psychomotor Performance
- RNA, Small Interfering -- genetics
- Rats
- Rats, Wistar
- Substantia Nigra -- pathology
- Tyrosine 3-Monooxygenase
- rho-Associated Kinases -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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