Tumour MLH1 promoter region methylation testing is an effective prescreen for Lynch Syndrome (HNPCC). [electronic resource]
Producer: 20150709Description: 789-96 p. digitalISSN:- 1468-6244
- Adaptor Proteins, Signal Transducing -- genetics
- Adult
- Alleles
- Brain Neoplasms -- genetics
- Colorectal Neoplasms -- genetics
- Colorectal Neoplasms, Hereditary Nonpolyposis -- diagnosis
- CpG Islands
- DNA Methylation
- Genetic Testing -- methods
- Heterozygote
- Humans
- Middle Aged
- MutL Protein Homolog 1
- Mutation
- Neoplasms -- genetics
- Neoplastic Syndromes, Hereditary -- genetics
- Nuclear Proteins -- genetics
- Promoter Regions, Genetic
- Proto-Oncogene Proteins B-raf -- genetics
- Sensitivity and Specificity
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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