Protein tyrosine phosphatase PTPN3 inhibits lung cancer cell proliferation and migration by promoting EGFR endocytic degradation. [electronic resource]
Producer: 20151016Description: 3791-803 p. digitalISSN:- 1476-5594
- Adaptor Proteins, Signal Transducing -- genetics
- Animals
- Animals, Genetically Modified
- Carcinoma, Non-Small-Cell Lung -- genetics
- Cell Line
- Cell Line, Tumor
- Cell Movement
- Cell Proliferation
- Endocytosis
- ErbB Receptors -- metabolism
- Female
- HEK293 Cells
- Humans
- Immunoblotting
- Lung Neoplasms -- genetics
- Male
- Membrane Microdomains -- metabolism
- Mice, Inbred BALB C
- Mice, Nude
- Microscopy, Confocal
- Mutation
- Phosphorylation
- Protein Tyrosine Phosphatase, Non-Receptor Type 3 -- genetics
- RNA Interference
- Transplantation, Heterologous
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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