A687V EZH2 is a driver of histone H3 lysine 27 (H3K27) hypertrimethylation. [electronic resource]
Producer: 20150811Description: 3062-73 p. digitalISSN:- 1538-8514
- Amino Acid Sequence
- Amino Acid Substitution
- Binding Sites
- Cell Line, Tumor
- Cluster Analysis
- Enhancer of Zeste Homolog 2 Protein
- Gene Expression
- Gene Expression Profiling
- Gene Silencing
- Heterozygote
- Histones -- metabolism
- Humans
- Lysine -- metabolism
- Methylation
- Models, Molecular
- Molecular Sequence Data
- Mutation
- Polycomb Repressive Complex 2 -- chemistry
- Precursor B-Cell Lymphoblastic Leukemia-Lymphoma -- genetics
- Protein Conformation
- Sequence Alignment
- Substrate Specificity
- Transcriptional Activation
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Publication Type: Journal Article
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