Deguelin, a selective silencer of the NPM1 mutant, potentiates apoptosis and induces differentiation in AML cells carrying the NPM1 mutation. [electronic resource]
Producer: 20150420Description: 201-10 p. digitalISSN:- 1432-0584
- Acute Disease
- Apoptosis -- drug effects
- Blotting, Western
- CCAAT-Enhancer-Binding Protein-alpha -- metabolism
- Caspase 6 -- metabolism
- Caspase 8 -- metabolism
- Cell Differentiation -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Cyclin-Dependent Kinase Inhibitor p21 -- metabolism
- Dose-Response Relationship, Drug
- Flow Cytometry
- Humans
- Leukemia, Myeloid -- genetics
- Mutant Proteins -- genetics
- Mutation
- Nuclear Proteins -- genetics
- Nucleophosmin
- RNA Interference
- Rotenone -- analogs & derivatives
- Tumor Suppressor Protein p53 -- metabolism
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.