ΔNp63 promotes stem cell activity in mammary gland development and basal-like breast cancer by enhancing Fzd7 expression and Wnt signalling. [electronic resource]
Producer: 20141215Description: 1004-15, 1-13 p. digitalISSN:- 1476-4679
- Animals
- Blotting, Western
- Breast Neoplasms -- genetics
- Cell Line, Tumor
- Epithelial Cells -- metabolism
- Frizzled Receptors -- genetics
- Gene Expression Regulation, Neoplastic
- Green Fluorescent Proteins -- genetics
- Humans
- Interleukin Receptor Common gamma Subunit -- deficiency
- Mammary Glands, Animal -- cytology
- Mammary Glands, Human -- cytology
- Mice, Inbred C57BL
- Mice, Inbred NOD
- Mice, Knockout
- Mice, SCID
- Mice, Transgenic
- Microscopy, Confocal
- Neoplastic Stem Cells -- metabolism
- Oligonucleotide Array Sequence Analysis
- Reverse Transcriptase Polymerase Chain Reaction
- Stem Cells -- cytology
- Transcription Factors -- genetics
- Transplantation, Heterologous
- Tumor Suppressor Proteins -- genetics
- Wnt Signaling Pathway
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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