BAY 87-2243, a novel inhibitor of hypoxia-induced gene activation, improves local tumor control after fractionated irradiation in a schedule-dependent manner in head and neck human xenografts. [electronic resource]
Producer: 20150511Description: 207 p. digitalISSN:- 1748-717X
- Animals
- Antineoplastic Agents -- pharmacology
- Blotting, Western
- Carcinoma, Squamous Cell -- pathology
- Cell Hypoxia -- drug effects
- Chemoradiotherapy -- methods
- Dose Fractionation, Radiation
- Head and Neck Neoplasms -- pathology
- Humans
- Hypoxia-Inducible Factor 1, alpha Subunit -- antagonists & inhibitors
- Mice
- Mice, Nude
- Oxadiazoles -- pharmacology
- Pyrazoles -- pharmacology
- Radiation-Sensitizing Agents -- pharmacology
- Squamous Cell Carcinoma of Head and Neck
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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