Suppression of mTORC1 activation in acid-α-glucosidase-deficient cells and mice is ameliorated by leucine supplementation. [electronic resource]
Producer: 20150117Description: R1251-9 p. digitalISSN:- 1522-1490
- Animals
- Cell Line
- Dietary Supplements
- Dipeptides -- pharmacology
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Fibroblasts -- drug effects
- Glycogen -- metabolism
- Glycogen Storage Disease Type II -- drug therapy
- Humans
- Insulin -- pharmacology
- Kyphosis -- enzymology
- Lysosomes -- drug effects
- Mechanistic Target of Rapamycin Complex 1
- Mice, Inbred C57BL
- Mice, Knockout
- Motor Activity -- drug effects
- Multiprotein Complexes -- metabolism
- Muscle, Skeletal -- drug effects
- Muscular Atrophy -- enzymology
- Myoblasts -- drug effects
- RNA Interference
- TOR Serine-Threonine Kinases -- metabolism
- Transfection
- alpha-Glucosidases -- deficiency
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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