Transfection of poly(I:C) can induce reactive oxygen species-triggered apoptosis and interferon-β-mediated growth arrest in human renal cell carcinoma cells via innate adjuvant receptors and the 2-5A system. [electronic resource]
Producer: 20160506Description: 217 p. digitalISSN:- 1476-4598
- Acetylcysteine -- pharmacology
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Carcinoma, Renal Cell -- drug therapy
- Cell Cycle -- drug effects
- Cell Line, Tumor
- Endoribonucleases -- metabolism
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Interferon-beta -- metabolism
- Kidney Neoplasms -- drug therapy
- Membrane Potential, Mitochondrial -- drug effects
- Poly I-C -- pharmacology
- Reactive Oxygen Species -- metabolism
- Transfection
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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