Identification of positive allosteric modulators VU0155094 (ML397) and VU0422288 (ML396) reveals new insights into the biology of metabotropic glutamate receptor 7. [electronic resource]
Producer: 20150825Description: 1221-37 p. digitalISSN:- 1948-7193
- Acetanilides -- chemistry
- Animals
- Benzoates -- pharmacology
- CHO Cells
- Calcium -- metabolism
- Cricetulus
- Dose-Response Relationship, Drug
- Excitatory Amino Acid Agents -- chemistry
- Excitatory Postsynaptic Potentials -- drug effects
- G Protein-Coupled Inwardly-Rectifying Potassium Channels -- genetics
- Glutamic Acid -- pharmacology
- Glycine -- analogs & derivatives
- HEK293 Cells
- Hippocampus -- drug effects
- Humans
- In Vitro Techniques
- Male
- Mice, Inbred C57BL
- Picolinic Acids -- chemistry
- Propionates -- pharmacology
- Pyrroles -- chemistry
- Rats
- Receptors, Metabotropic Glutamate -- genetics
- Structure-Activity Relationship
- Thallium -- metabolism
- Transfection
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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