Design and synthesis of a cell-permeable, drug-like small molecule inhibitor targeting the polo-box domain of polo-like kinase 1. [electronic resource]
Producer: 20151026Description: e107432 p. digitalISSN:- 1932-6203
- Antineoplastic Agents -- chemical synthesis
- Benzimidazoles -- chemical synthesis
- Catalytic Domain
- Cell Cycle Proteins -- antagonists & inhibitors
- Cell Membrane Permeability
- Drug Design
- Drug Screening Assays, Antitumor
- HeLa Cells
- Humans
- Models, Molecular
- Organophosphates -- chemical synthesis
- Protein Binding
- Protein Kinase Inhibitors -- chemical synthesis
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- Proto-Oncogene Proteins -- antagonists & inhibitors
- Polo-Like Kinase 1
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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