Loss of TRB3 alters dynamics of MLK3-JNK signaling and inhibits cytokine-activated pancreatic beta cell death. [electronic resource]
Producer: 20150212Description: 29994-30004 p. digitalISSN:- 1083-351X
- Animals
- Cell Cycle Proteins -- deficiency
- Cell Death -- drug effects
- Cell Line, Tumor
- Cytokines -- pharmacology
- Enzyme Activation -- drug effects
- Enzyme Stability -- drug effects
- Humans
- Insulin -- pharmacology
- Insulin-Secreting Cells -- drug effects
- JNK Mitogen-Activated Protein Kinases -- metabolism
- Lysine -- metabolism
- MAP Kinase Kinase Kinases -- metabolism
- MAP Kinase Signaling System -- drug effects
- Mice
- Mutation -- genetics
- Phosphorylation -- drug effects
- Phosphothreonine -- metabolism
- Polyubiquitin -- metabolism
- Proto-Oncogene Proteins c-akt -- metabolism
- Ubiquitination -- drug effects
- Mitogen-Activated Protein Kinase Kinase Kinase 11
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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