Grape seed proanthocyanidins (GSPs) inhibit the growth of cervical cancer by inducing apoptosis mediated by the mitochondrial pathway. [electronic resource]
Producer: 20151204Description: e107045 p. digitalISSN:- 1932-6203
- Animals
- Antineoplastic Agents, Phytogenic -- pharmacology
- Apoptosis -- drug effects
- Caspase 3 -- genetics
- Cell Line, Tumor
- Female
- Gene Expression Regulation, Neoplastic
- Grape Seed Extract -- pharmacology
- Humans
- Membrane Potential, Mitochondrial -- drug effects
- Mice
- Mice, Nude
- Mitochondria -- drug effects
- Proanthocyanidins -- pharmacology
- Proto-Oncogene Proteins c-bcl-2 -- antagonists & inhibitors
- Signal Transduction -- drug effects
- Transplantation, Heterotopic
- Tumor Burden -- drug effects
- Uterine Cervical Neoplasms -- drug therapy
- Xenograft Model Antitumor Assays
- bcl-2 Homologous Antagonist-Killer Protein -- agonists
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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