Loss of Tribbles pseudokinase-3 promotes Akt-driven tumorigenesis via FOXO inactivation. [electronic resource]
Producer: 20150729Description: 131-44 p. digitalISSN:- 1476-5403
- Animals
- Cell Cycle Proteins -- genetics
- Cell Line, Tumor
- Forkhead Box Protein O3
- Forkhead Transcription Factors -- genetics
- Humans
- Mechanistic Target of Rapamycin Complex 2
- Mice
- Mice, Knockout
- Mice, Nude
- Multiprotein Complexes -- genetics
- Neoplasms -- genetics
- Phosphorylation -- genetics
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- Proto-Oncogene Proteins c-akt -- genetics
- Repressor Proteins -- genetics
- TOR Serine-Threonine Kinases -- genetics
- Tumor Suppressor Proteins -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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