Targeting the actin cytoskeleton: selective antitumor action via trapping PKCɛ. [electronic resource]
Producer: 20150908Description: e1398 p. digitalISSN:- 2041-4889
- Actin Cytoskeleton -- drug effects
- Actins -- genetics
- Animals
- Antineoplastic Agents -- therapeutic use
- Apoptosis -- drug effects
- Binding Sites
- Breast Neoplasms -- drug therapy
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cytochromes c -- metabolism
- Depsipeptides -- therapeutic use
- Female
- Fluorescence Recovery After Photobleaching
- Hexokinase -- metabolism
- Humans
- MCF-7 Cells
- Membrane Potential, Mitochondrial -- drug effects
- Mice
- Mice, SCID
- Mitochondria -- metabolism
- Phosphatidylserines -- pharmacology
- Protein Kinase C -- metabolism
- Signal Transduction
- Transplantation, Heterologous
- Voltage-Dependent Anion Channels -- metabolism
- bcl-Associated Death Protein -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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