Restricted isotype, distinct variable gene usage, and high rate of gp120 specificity of HIV-1 envelope-specific B cells in colostrum compared with those in blood of HIV-1-infected, lactating African women. [electronic resource]
Producer: 20151026Description: 316-26 p. digitalISSN:- 1935-3456
- Black or African American
- Antibody Formation -- immunology
- B-Lymphocytes -- cytology
- CD4 Lymphocyte Count
- Clonal Evolution
- Colostrum -- cytology
- Complementarity Determining Regions -- genetics
- Epitopes, B-Lymphocyte -- immunology
- Female
- HIV Antibodies -- immunology
- HIV Envelope Protein gp120 -- immunology
- HIV Envelope Protein gp41 -- immunology
- HIV Infections -- blood
- HIV-1 -- immunology
- Humans
- Immunoglobulin G -- blood
- Immunoglobulin Heavy Chains -- genetics
- Immunoglobulin Variable Region -- genetics
- Immunologic Memory
- Immunophenotyping
- Infectious Disease Transmission, Vertical
- Lactation
- Mutation Rate
- Phenotype
- Somatic Hypermutation, Immunoglobulin
- Viral Load
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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