Upregulation of immunoproteasome subunits in myositis indicates active inflammation with involvement of antigen presenting cells, CD8 T-cells and IFNΓ. [electronic resource]
Producer: 20150411Description: e104048 p. digitalISSN:- 1932-6203
- Adult
- Aged
- CD8-Positive T-Lymphocytes -- enzymology
- Dendritic Cells -- enzymology
- Female
- Gene Expression Regulation, Enzymologic -- immunology
- Humans
- Interferon Regulatory Factor-1 -- immunology
- Interferon-gamma -- biosynthesis
- Male
- Middle Aged
- Muscle Proteins -- biosynthesis
- Myositis -- enzymology
- Proteasome Endopeptidase Complex -- biosynthesis
- STAT1 Transcription Factor -- immunology
- Up-Regulation -- immunology
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Publication Type: Clinical Trial; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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