Downregulation of COX-2 and CYP 4A signaling by isoliquiritigenin inhibits human breast cancer metastasis through preventing anoikis resistance, migration and invasion. [electronic resource]
Producer: 20141121Description: 10-20 p. digitalISSN:- 1096-0333
- Animals
- Anoikis -- drug effects
- Breast Neoplasms -- drug therapy
- Cell Line, Tumor
- Cell Movement -- drug effects
- Chalcones -- pharmacology
- Cyclooxygenase 2 -- metabolism
- Cytochrome P-450 CYP4A -- antagonists & inhibitors
- Down-Regulation -- drug effects
- Enzyme Inhibitors -- pharmacology
- Female
- Glycyrrhiza
- Humans
- Mice
- Mice, Inbred BALB C
- Mice, Nude
- Neoplasm Invasiveness -- prevention & control
- Plant Extracts -- isolation & purification
- Random Allocation
- Signal Transduction -- drug effects
- Xenograft Model Antitumor Assays -- methods
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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