Dose-dependent differential response of mammalian cells to cytoplasmic stress is mediated through the heme-regulated eIF2α kinase. [electronic resource]
Producer: 20150521Description: 186-97 p. digitalISSN:- 1878-5875
- Apoptosis -- drug effects
- Blotting, Western
- Cell Cycle -- drug effects
- Cell Proliferation -- drug effects
- Cells, Cultured
- Cytoplasm -- drug effects
- Databases, Protein
- Dose-Response Relationship, Drug
- HeLa Cells
- Humans
- K562 Cells
- Organometallic Compounds -- pharmacology
- Phosphatidylinositol 3-Kinases -- genetics
- Phosphorylation
- Protein Interaction Domains and Motifs
- Proto-Oncogene Proteins c-akt -- genetics
- RNA, Messenger -- genetics
- RNA, Small Interfering -- genetics
- Real-Time Polymerase Chain Reaction
- Reverse Transcriptase Polymerase Chain Reaction
- Stress, Physiological
- eIF-2 Kinase -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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