Novel dual endothelin receptor antagonist macitentan reverses severe pulmonary arterial hypertension in rats. [electronic resource]
Producer: 20150713Description: 473-80 p. digitalISSN:- 1533-4023
- Animals
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Endothelin A Receptor Antagonists -- administration & dosage
- Endothelin B Receptor Antagonists -- administration & dosage
- Hypertension, Pulmonary -- drug therapy
- Hypertrophy, Right Ventricular -- drug therapy
- Indoles -- pharmacology
- Male
- Pyrimidines -- administration & dosage
- Pyrroles -- pharmacology
- Rats
- Rats, Sprague-Dawley
- Severity of Illness Index
- Sulfonamides -- administration & dosage
- Time Factors
- Vascular Endothelial Growth Factor A -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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