Dexmedetomidine inhibits inducible nitric oxide synthase in lipopolysaccharide-stimulated microglia by suppression of extracellular signal-regulated kinase. [electronic resource]
Producer: 20150820Description: 238-45 p. digitalISSN:- 1743-1328
- Animals
- Anti-Inflammatory Agents, Non-Steroidal -- pharmacology
- Blotting, Western
- Cell Line
- Dexmedetomidine -- pharmacology
- Dose-Response Relationship, Drug
- Extracellular Signal-Regulated MAP Kinases -- metabolism
- Flavonoids -- pharmacology
- JNK Mitogen-Activated Protein Kinases -- metabolism
- Lipopolysaccharides -- toxicity
- MAP Kinase Signaling System -- drug effects
- Mice
- Microglia -- drug effects
- Nitric Oxide -- metabolism
- Nitric Oxide Synthase Type II -- antagonists & inhibitors
- Protein Kinase Inhibitors -- pharmacology
- Rats
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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