Targeted deletion and lipidomic analysis identify epithelial cell COX-2 as a major driver of chemically induced skin cancer. [electronic resource]
Producer: 20150722Description: 1677-88 p. digitalISSN:- 1557-3125
- 9,10-Dimethyl-1,2-benzanthracene
- Animals
- Cell Differentiation
- Cell Proliferation
- Cyclooxygenase 2 -- metabolism
- Eicosanoids -- metabolism
- Epidermis -- pathology
- Epithelial Cells -- enzymology
- Gene Deletion
- Gene Targeting
- Hyperplasia
- Keratinocytes -- enzymology
- Lipid Metabolism
- Macrophages -- pathology
- Mice
- Myeloid Cells -- enzymology
- Papilloma -- pathology
- Skin -- blood supply
- Skin Neoplasms -- chemically induced
- Tetradecanoylphorbol Acetate
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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