Inhibitors of histone deacetylases enhance neurotoxicity of DNA damage. [electronic resource]
Producer: 20150720Description: 727-41 p. digitalISSN:- 1559-1174
- Animals
- Animals, Newborn
- Antineoplastic Agents -- toxicity
- Apoptosis -- drug effects
- Benzamides -- pharmacology
- Camptothecin -- toxicity
- Cells, Cultured
- Cerebral Cortex -- cytology
- Cisplatin -- toxicity
- DNA Breaks, Double-Stranded -- drug effects
- Dizocilpine Maleate -- toxicity
- Etoposide -- administration & dosage
- Genes, p53
- Histone Deacetylase 1 -- antagonists & inhibitors
- Histone Deacetylase Inhibitors -- pharmacology
- Hydroxamic Acids -- pharmacology
- Injections, Intraventricular
- Neurons -- drug effects
- Phosphorylation -- drug effects
- Point Mutation
- Protein Processing, Post-Translational -- drug effects
- Pyridines -- pharmacology
- Rats
- Rats, Sprague-Dawley
- Tumor Suppressor Protein p53 -- metabolism
- Vorinostat
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Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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