Genomic models of short-term exposure accurately predict long-term chemical carcinogenicity and identify putative mechanisms of action. [electronic resource]
Producer: 20150421Description: e102579 p. digitalISSN:- 1932-6203
- Animals
- Area Under Curve
- Carcinogenicity Tests -- methods
- Carcinogens -- toxicity
- DNA Damage
- DNA Repair
- Databases, Factual
- Drugs, Investigational -- toxicity
- Gene Expression -- drug effects
- Gene Expression Profiling
- Male
- Models, Genetic
- Organ Specificity
- Peroxisome Proliferator-Activated Receptors -- genetics
- Quantitative Structure-Activity Relationship
- Rats
- Receptors, Aryl Hydrocarbon -- genetics
- Sensitivity and Specificity
- Toxicogenetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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