The ribonuclease activity of SAMHD1 is required for HIV-1 restriction. [electronic resource]
Producer: 20141010Description: 936-41 p. digitalISSN:- 1546-170X
- Autoimmune Diseases of the Nervous System -- genetics
- Base Sequence
- Binding Sites -- genetics
- CD4-Positive T-Lymphocytes
- Cell Line, Tumor
- HIV Infections -- genetics
- HIV-1 -- physiology
- HeLa Cells
- Humans
- Macrophages
- Monomeric GTP-Binding Proteins -- genetics
- Mutation
- Nervous System Malformations -- genetics
- Phosphorylation
- RNA Interference
- RNA, Small Interfering -- genetics
- RNA, Viral -- genetics
- Ribonucleases -- metabolism
- SAM Domain and HD Domain-Containing Protein 1
- Sequence Analysis, RNA
- Virus Replication
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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