PP242 suppresses cell proliferation, metastasis, and angiogenesis of gastric cancer through inhibition of the PI3K/AKT/mTOR pathway. [electronic resource]
Producer: 20160510Description: 1129-40 p. digitalISSN:- 1473-5741
- Adenocarcinoma -- blood supply
- Aged
- Antineoplastic Agents -- pharmacology
- Cell Line, Tumor
- Cell Movement -- drug effects
- Cell Proliferation -- drug effects
- Female
- Human Umbilical Vein Endothelial Cells -- physiology
- Humans
- Indoles -- pharmacology
- Male
- Mechanistic Target of Rapamycin Complex 1
- Mechanistic Target of Rapamycin Complex 2
- Middle Aged
- Multiprotein Complexes -- metabolism
- Neoplasm Invasiveness -- pathology
- Neoplasm Metastasis
- Neovascularization, Pathologic -- metabolism
- Oncogene Protein v-akt -- metabolism
- Phosphatidylinositol 3-Kinases -- metabolism
- Phosphorylation
- Purines -- pharmacology
- Ribosomal Protein S6 Kinases, 70-kDa -- metabolism
- Signal Transduction
- Stomach Neoplasms -- blood supply
- TOR Serine-Threonine Kinases -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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