Pax6 regulates the expression of Dkk3 in murine and human cell lines, and altered responses to Wnt signaling are shown in FlpIn-3T3 cells stably expressing either the Pax6 or the Pax6(5a) isoform. [electronic resource]
Producer: 20151123Description: e102559 p. digitalISSN:- 1932-6203
- 3T3 Cells
- Adaptor Proteins, Signal Transducing
- Animals
- Base Sequence
- Blotting, Western
- Chemokines
- Eye Proteins -- metabolism
- Gene Expression Regulation -- physiology
- Gene Knockdown Techniques
- Glycogen Synthase Kinase 3 -- metabolism
- Glycogen Synthase Kinase 3 beta
- Homeodomain Proteins -- metabolism
- Humans
- Intercellular Signaling Peptides and Proteins -- genetics
- Mice
- Molecular Sequence Data
- PAX6 Transcription Factor
- Paired Box Transcription Factors -- metabolism
- Promoter Regions, Genetic -- genetics
- Protein Isoforms -- metabolism
- Repressor Proteins -- metabolism
- Reverse Transcriptase Polymerase Chain Reaction
- Sequence Alignment
- Wnt Signaling Pathway -- physiology
- beta Catenin -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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