Endogenously secreted IL-4 is required for mouse thymocytes to become cytotoxic. Human, but not mouse, IL-2 induces a functionally immature thymic subset to secrete IL-4 and become CTL. [electronic resource]
Producer: 19901011Description: 478-84 p. digitalISSN:- 0019-2805
- Animals
- Cell Differentiation -- immunology
- Cell Division -- immunology
- Cells, Cultured
- Humans
- Interleukin-2 -- immunology
- Interleukin-4 -- biosynthesis
- Lectins -- analysis
- Mice
- Mice, Inbred Strains
- Sialic Acid Binding Immunoglobulin-like Lectins
- T-Lymphocytes -- cytology
- T-Lymphocytes, Cytotoxic -- immunology
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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