Therapeutic effect of nanogel-based delivery of soluble FGFR2 with S252W mutation on craniosynostosis. [electronic resource]
Producer: 20150330Description: e101693 p. digitalISSN:- 1932-6203
- Acrocephalosyndactylia -- genetics
- Amino Acid Substitution
- Animals
- Calcification, Physiologic -- drug effects
- Cell Differentiation -- drug effects
- Cell Line
- Codon
- Cranial Sutures -- abnormalities
- Disease Models, Animal
- Drug Delivery Systems
- Female
- Fibroblast Growth Factor 10 -- genetics
- Fibroblast Growth Factor 2 -- metabolism
- Gene Expression
- Male
- Mice
- Mice, Transgenic
- Mutation
- Nanogels
- Osteoblasts -- cytology
- Phenotype
- Polyethylene Glycols -- administration & dosage
- Polyethyleneimine -- administration & dosage
- Protein Binding
- RNA-Binding Proteins -- genetics
- Receptor, Fibroblast Growth Factor, Type 2 -- administration & dosage
- Recombinant Proteins -- administration & dosage
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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