Periostin promotes liver steatosis and hypertriglyceridemia through downregulation of PPARα. [electronic resource]
Producer: 20150218Description: 3501-13 p. digitalISSN:- 1558-8238
- Animals
- Cell Adhesion Molecules -- deficiency
- Cross-Sectional Studies
- Down-Regulation
- Fatty Liver -- etiology
- Female
- Hep G2 Cells
- Humans
- Hypertriglyceridemia -- etiology
- Integrin alpha6beta4 -- metabolism
- Liver -- metabolism
- MAP Kinase Signaling System
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Mice, Obese
- Models, Biological
- Nuclear Receptor Subfamily 1, Group F, Member 1 -- metabolism
- Obesity -- complications
- PPAR alpha -- genetics
- Promoter Regions, Genetic
- RNA, Messenger -- genetics
- Triglycerides -- blood
- Up-Regulation
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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