The proteasome inhibitor, MG132, attenuates diabetic nephropathy by inhibiting SnoN degradation in vivo and in vitro. [electronic resource]
Producer: 20150306Description: 684765 p. digitalISSN:- 2314-6141
- Animals
- Diabetic Nephropathies -- drug therapy
- Down-Regulation -- drug effects
- Glucose -- toxicity
- Kidney Function Tests
- Kidney Glomerulus -- pathology
- Leupeptins -- pharmacology
- Male
- Mesangial Cells -- drug effects
- Nerve Tissue Proteins -- metabolism
- Proteasome Inhibitors -- pharmacology
- Proteinuria -- complications
- Proteolysis -- drug effects
- Rats, Wistar
- Streptozocin
- Transcription Factors -- metabolism
- Transforming Growth Factor beta -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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