Dynamic and coordinated regulation of KEAP1-NRF2-ARE and p53/p21 signaling pathways is associated with acetaminophen injury responsive liver regeneration. [electronic resource]
Producer: 20150330Description: 1532-9 p. digitalISSN:- 1521-009X
- Acetaminophen -- adverse effects
- Adaptor Proteins, Signal Transducing -- metabolism
- Animals
- Carboxylic Ester Hydrolases -- metabolism
- Cell Proliferation -- physiology
- Chemical and Drug Induced Liver Injury -- metabolism
- Cyclin D1 -- metabolism
- Cyclin-Dependent Kinase 4 -- metabolism
- Cyclin-Dependent Kinase Inhibitor p21 -- metabolism
- Cytoskeletal Proteins -- metabolism
- Hepatocytes -- metabolism
- Kelch-Like ECH-Associated Protein 1
- Liver -- drug effects
- Liver Regeneration -- physiology
- Male
- Mice
- Mice, Inbred C57BL
- NF-E2-Related Factor 2 -- metabolism
- Proliferating Cell Nuclear Antigen -- metabolism
- Signal Transduction -- physiology
- Tumor Suppressor Protein p53 -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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