Genotyping cancer-associated genes in chordoma identifies mutations in oncogenes and areas of chromosomal loss involving CDKN2A, PTEN, and SMARCB1. [electronic resource]
Producer: 20151103Description: e101283 p. digitalISSN:- 1932-6203
- Adult
- Aged
- Aged, 80 and over
- Anaplastic Lymphoma Kinase
- Chordoma -- genetics
- Chromosomal Proteins, Non-Histone -- genetics
- Chromosome Deletion
- Class I Phosphatidylinositol 3-Kinases
- Cyclin-Dependent Kinase Inhibitor p16 -- genetics
- DNA Mutational Analysis
- DNA-Binding Proteins -- genetics
- Female
- GTP Phosphohydrolases -- genetics
- Genes, Neoplasm
- Genotyping Techniques
- Humans
- Male
- Membrane Proteins -- genetics
- Middle Aged
- Mutation
- Oncogenes
- PTEN Phosphohydrolase -- genetics
- Phosphatidylinositol 3-Kinases -- genetics
- Receptor Protein-Tyrosine Kinases -- genetics
- SMARCB1 Protein
- Transcription Factors -- genetics
- beta Catenin -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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