Dissociation of pentameric to monomeric C-reactive protein localizes and aggravates inflammation: in vivo proof of a powerful proinflammatory mechanism and a new anti-inflammatory strategy. [electronic resource]
Producer: 20140902Description: 35-50 p. digitalISSN:- 1524-4539
- Animals
- Anti-Inflammatory Agents -- pharmacology
- Biopolymers
- C-Reactive Protein -- chemistry
- Carrier Proteins -- chemistry
- Cell Adhesion -- drug effects
- Cell Membrane -- drug effects
- Chemotaxis, Leukocyte
- Complement Activation
- Endothelial Cells -- drug effects
- Hexanes -- pharmacology
- Humans
- Inflammation -- drug therapy
- Leukocyte Rolling -- drug effects
- Lipopolysaccharides -- toxicity
- Lysophosphatidylcholines -- metabolism
- Male
- Membrane Lipids -- metabolism
- Muscle, Skeletal -- blood supply
- Myocardial Infarction -- metabolism
- Myositis -- chemically induced
- Phospholipase A2 Inhibitors -- pharmacology
- Phospholipases A2 -- metabolism
- Phosphorylcholine -- analogs & derivatives
- Protein Structure, Quaternary
- Random Allocation
- Rats
- Rats, Wistar
- Receptors, IgG -- physiology
- Reperfusion Injury -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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