Preclinical studies of amixicile, a systemic therapeutic developed for treatment of Clostridium difficile infections that also shows efficacy against Helicobacter pylori. [electronic resource]
Producer: 20150828Description: 4703-12 p. digitalISSN:- 1098-6596
- Animals
- Anti-Bacterial Agents -- blood
- Area Under Curve
- Benzamides -- blood
- Biological Availability
- Cell Line
- Cell Survival -- drug effects
- Dogs
- Drug Evaluation, Preclinical
- Half-Life
- Helicobacter Infections -- blood
- Helicobacter pylori -- drug effects
- Hepatocytes -- cytology
- Humans
- Male
- Microbial Sensitivity Tests
- Microbiota -- drug effects
- Microsomes, Liver -- drug effects
- Pyruvate Synthase -- metabolism
- Rats
- Thiamine Pyrophosphate -- metabolism
- Thiazoles -- blood
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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