Hepatic toxicity of dronedarone in mice: role of mitochondrial β-oxidation. [electronic resource]
Producer: 20140926Description: 1-9 p. digitalISSN:- 1879-3185
- Alanine Transaminase -- blood
- Amiodarone -- analogs & derivatives
- Animals
- Anti-Arrhythmia Agents -- toxicity
- Disease Models, Animal
- Dronedarone
- Fatty Acids -- metabolism
- Fatty Liver
- Liver -- anatomy & histology
- Male
- Membrane Potential, Mitochondrial
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Mitochondria, Liver -- drug effects
- Oxidation-Reduction
- Oxygen Consumption
- Palmitic Acid -- pharmacology
- Palmitoylcarnitine -- pharmacology
- Proto-Oncogene Proteins c-bcl-2 -- genetics
- RNA, Messenger -- metabolism
- bcl-2-Associated X Protein -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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