Exome sequencing identifies somatic gain-of-function PPM1D mutations in brainstem gliomas. [electronic resource]
Producer: 20140904Description: 726-30 p. digitalISSN:- 1546-1718
- Brain Stem Neoplasms -- genetics
- Cell Proliferation
- Cells, Cultured
- Checkpoint Kinase 2 -- metabolism
- DNA Copy Number Variations
- DNA Methylation
- Exome -- genetics
- Gene Expression Profiling
- Glioma -- genetics
- High-Throughput Nucleotide Sequencing
- Histones -- metabolism
- Humans
- Immunoblotting
- Immunoenzyme Techniques
- Immunoprecipitation
- Mutation -- genetics
- Phosphoprotein Phosphatases -- genetics
- Prognosis
- Protein Phosphatase 2C
- Survival Rate
- Tumor Stem Cell Assay
- Tumor Suppressor Protein p53 -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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