SETD2 is required for DNA double-strand break repair and activation of the p53-mediated checkpoint. [electronic resource]
Producer: 20151123Description: e02482 p. digitalISSN:- 2050-084X
- Ataxia Telangiectasia Mutated Proteins -- metabolism
- Carcinoma, Renal Cell -- metabolism
- Cell Cycle Checkpoints -- genetics
- Cell Line, Tumor
- Cell Survival
- DNA Breaks, Double-Stranded
- DNA Repair
- Histone-Lysine N-Methyltransferase -- genetics
- Humans
- Intracellular Signaling Peptides and Proteins -- metabolism
- Kidney Neoplasms -- metabolism
- Mutation -- genetics
- Protein Binding
- Rad51 Recombinase -- metabolism
- Recombination, Genetic
- Recombinational DNA Repair
- Replication Protein A -- metabolism
- Signal Transduction -- genetics
- Tumor Suppressor Protein p53 -- metabolism
- Tumor Suppressor p53-Binding Protein 1
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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