Targeted inhibition of mTORC2 prevents osteosarcoma cell migration and promotes apoptosis. [electronic resource]
Producer: 20150114Description: 382-8 p. digitalISSN:- 1791-2431
- Antineoplastic Combined Chemotherapy Protocols
- Apoptosis -- drug effects
- Carrier Proteins -- genetics
- Cell Line, Tumor
- Cell Movement -- drug effects
- Cisplatin -- pharmacology
- Gene Knockdown Techniques
- Humans
- Indoles -- pharmacology
- Mechanistic Target of Rapamycin Complex 1
- Mechanistic Target of Rapamycin Complex 2
- Multiprotein Complexes -- antagonists & inhibitors
- Osteosarcoma -- metabolism
- Purines -- pharmacology
- RNA, Small Interfering -- pharmacology
- Rapamycin-Insensitive Companion of mTOR Protein
- Sirolimus -- pharmacology
- TOR Serine-Threonine Kinases -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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