Lysyl oxidases play a causal role in vascular remodeling in clinical and experimental pulmonary arterial hypertension. [electronic resource]
Producer: 20140826Description: 1446-58 p. digitalISSN:- 1524-4636
- Adult
- Aged, 80 and over
- Animals
- Antihypertensive Agents -- pharmacology
- Case-Control Studies
- Cell Hypoxia
- Cells, Cultured
- Collagen -- metabolism
- Disease Models, Animal
- Elastin -- metabolism
- Enzyme Inhibitors -- pharmacology
- Familial Primary Pulmonary Hypertension
- Female
- Fibroblasts -- enzymology
- Gene Expression Regulation, Enzymologic
- Humans
- Hypertension, Pulmonary -- drug therapy
- Hypertrophy, Right Ventricular -- enzymology
- Hypoxia -- complications
- Isoenzymes
- Male
- Mice
- Middle Aged
- Monocrotaline
- Muscle, Smooth, Vascular -- enzymology
- Myocytes, Smooth Muscle -- enzymology
- Protein-Lysine 6-Oxidase -- antagonists & inhibitors
- Pulmonary Artery -- drug effects
- RNA, Messenger -- metabolism
- Rats
- Ventricular Dysfunction, Right -- enzymology
- Young Adult
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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