Structure of the unique SEFIR domain from human interleukin 17 receptor A reveals a composite ligand-binding site containing a conserved α-helix for Act1 binding and IL-17 signaling. [electronic resource]
Producer: 20150513Description: 1476-83 p. digitalISSN:- 1399-0047
- Adaptor Proteins, Signal Transducing
- Amino Acid Motifs
- Amino Acid Sequence
- Binding Sites
- Conserved Sequence
- Crystallography, X-Ray
- Humans
- Interleukin-17 -- metabolism
- Ligands
- Mutation
- Protein Structure, Tertiary
- Receptors, Interleukin-17 -- chemistry
- Signal Transduction
- Tumor Necrosis Factor Receptor-Associated Peptides and Proteins -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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