Oligosaccharide G19 inhibits U-87 MG human glioma cells growth in vitro and in vivo by targeting epidermal growth factor (EGF) and activating p53/p21 signaling. [electronic resource]
Producer: 20150417Description: 748-65 p. digitalISSN:- 1460-2423
- Antineoplastic Agents, Phytogenic -- pharmacology
- Apoptosis -- drug effects
- Cell Cycle -- drug effects
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Cyclin-Dependent Kinase Inhibitor p21 -- metabolism
- Dose-Response Relationship, Drug
- Drug Screening Assays, Antitumor
- Epidermal Growth Factor -- metabolism
- Glioma -- drug therapy
- Humans
- Molecular Targeted Therapy
- Oligosaccharides -- pharmacology
- Rhodophyta -- chemistry
- Signal Transduction -- drug effects
- Structure-Activity Relationship
- Tumor Cells, Cultured
- Tumor Suppressor Protein p53 -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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