RNAi silencing of P/Q-type calcium channels in Purkinje neurons of adult mouse leads to episodic ataxia type 2. [electronic resource]
Producer: 20150511Description: 47-56 p. digitalISSN:- 1095-953X
- Animals
- Ataxia -- etiology
- Calcium Channels, N-Type -- genetics
- Cerebellum -- metabolism
- Disease Models, Animal
- Green Fluorescent Proteins -- genetics
- HEK293 Cells
- Humans
- Male
- Membrane Potentials -- drug effects
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Movement -- physiology
- Nystagmus, Pathologic -- etiology
- Postural Balance -- genetics
- Purkinje Cells -- metabolism
- RNA Interference -- physiology
- RNA, Small Interfering -- genetics
- Transduction, Genetic
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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