MEK inhibition, alone or in combination with BRAF inhibition, affects multiple functions of isolated normal human lymphocytes and dendritic cells. [electronic resource]
Producer: 20141203Description: 351-60 p. digitalISSN:- 2326-6074
- Antigens, Neoplasm -- immunology
- Cell Differentiation
- Cell Proliferation -- drug effects
- Cross-Priming -- immunology
- Cytokines -- biosynthesis
- Dendritic Cells -- cytology
- Epitopes, T-Lymphocyte -- immunology
- Humans
- Imidazoles -- pharmacology
- Lipopolysaccharides -- immunology
- Lymphocyte Activation -- drug effects
- Lymphocyte Subsets -- drug effects
- Lymphocytes -- drug effects
- Mitogen-Activated Protein Kinase Kinases -- antagonists & inhibitors
- Oximes -- pharmacology
- Protein Kinase Inhibitors -- pharmacology
- Proto-Oncogene Proteins B-raf -- antagonists & inhibitors
- Pyridones -- pharmacology
- Pyrimidinones -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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